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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2supercoiled DNA + ATP + H2O dATP can substitute for ATP Bos taurus relaxed DNA + ADP + phosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2supercoiled DNA + ATP + H2O under optimal conditions the enzyme relaxes all supercoils prior to dissociation of the enzyme from DNA eukaryota relaxed DNA + ADP + phosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2supercoiled DNA + ATP + H2O positive supercoils are relaxed in presence of beta,gamma-imido ATP Bacteria relaxed DNA + ADP + phosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2supercoiled DNA + ATP + H2O relaxation of negatively supercoiled DNA Saccharomyces cerevisiae relaxed DNA + ADP + phosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2supercoiled DNA + ATP + H2O under optimal conditions relaxation of negatively supercoiled DNA occurs in a highly processive manner eukaryota relaxed DNA + ADP + phosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2supercoiled DNA + ATP + H2O DNA cleavage by topo VI generates two-nucleotide 5'-protruding ends Saccharolobus shibatae relaxed DNA + ADP + phosphate - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2supercoiled DNA + ATP + H2O relaxation Sulfolobus sp. B12 relaxed DNA + ADP + phosphate ADP is cleaved to ADP and phosphate ?
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2supercoiled DNA + ATP + H2O ATP-dependent relaxation of negative and positive supercoils Sulfolobus sp. B12 relaxed DNA + ADP + phosphate ADP is cleaved to ADP and phosphate ?
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2supercoiled DNA + ATP + H2O substrate is supercoiled scpBR322 plasmid DNA. Topo2a creates transient breaks in supercoiled DNA in an ATP-dependent manner resulting in DNA relaxation Homo sapiens ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.2supercoiled dsDNA relaxation of supercoiled dsDNA, reaction mechanism Arabidopsis thaliana ? - ?
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