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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
3.4.22.49
cohesin + H2O
-
Arabidopsis thaliana
cleaved cohesin
-
?
3.4.22.49
cohesin + H2O
-
Schizosaccharomyces pombe
cleaved cohesin
-
?
3.4.22.49
cohesin + H2O
separase is required for sister chromatid separation during mitosis
Homo sapiens
cleaved cohesin
-
?
3.4.22.49
cohesin + H2O
separase, i.e. Esp1, is implicated in the removal of cohesin which links sister chromatids in the S-phase and is postulated to be a specific protease or a positive regulator of protease against cohesin
Saccharomyces cerevisiae
cleaved cohesin
-
?
3.4.22.49
cohesin + H2O
separase triggers anaphase by cohesin cleavage, and triggers the release and activation of the phosphatase Cdc14 independently of its protease activity
Saccharomyces cerevisiae
cleaved cohesin
-
?
3.4.22.49
cohesin + H2O
-
Drosophila melanogaster
?
-
?
3.4.22.49
cohesin + H2O
-
Chlamydomonas reinhardtii
?
-
?
3.4.22.49
cohesin + H2O
-
Mus musculus
?
-
?
3.4.22.49
cohesin + H2O
-
Homo sapiens
?
-
?
3.4.22.49
cohesin + H2O
-
Saccharomyces cerevisiae
?
-
?
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