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EC Number
Substrates
Commentary Substrates
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Commentary (Products)
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3.4.22.10
protein F1 + H2O
SpeB modulates fibronectin-dependent internalization of Streptococcus pyogenes by efficient proteolysis of cell-wall-anchored protein F1, e.g. in human pharyngeal epithelial cells Detroit 562, while proteins H and M1 are protected by plasma proteins, overview
Streptococcus pyogenes
?
-
?
3.4.22.10
protein F1 + H2O
cell-wall-anchored protein F1
Streptococcus pyogenes
?
-
?
3.4.22.10
protein H + H2O
-
Streptococcus pyogenes
?
-
?
3.4.22.10
resorufin-labeled casein + H2O
-
Streptococcus pyogenes
?
-
?
3.4.22.10
Sda1 + H2O
-
Streptococcus pyogenes
?
-
?
3.4.22.10
Slr + H2O
-
Streptococcus pyogenes
?
-
?
3.4.22.10
SmeZ + H2O
-
Streptococcus pyogenes
?
-
?
3.4.22.10
SpeBz + H2O
auto-cleavage sites are AIK-A, KVN-L, QIK-E, TYA-G, and EIK-Q
Streptococcus pyogenes
mature SpeB + ?
-
?
3.4.22.10
streptococcal mitogenic exotoxin SmeZ + H2O
cleaves between glutamate and glycine residues
Streptococcus pyogenes
?
-
?
3.4.22.10
streptococcal mitogenic exotoxin SpeG + H2O
partial degradation, SpeB cleaves between glutamate and glycine residues
Streptococcus pyogenes
?
-
?
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