EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   2.7.1.173 | more |
ADP binding mode, overview |
Homo sapiens |
? |
- |
? |
| 2.7.1.173 | more |
substrate specificity of recombinant Nrk1 and Nrk2, overview. Classification of Nrk1 as an nicotinic acid riboside and tiazofurin:ATP or GTP kinase, Nrk1 displays a 340fold preference for nicotinic acid riboside over cytidine in the KM term and a 500fold preference over either cytidine or uridine in the kcat/KM term. Poor cytidine monophosphate-forming activity of the enzyme. Structural basis of substrate specificity, overview. Base recognition in the Nrk1 nucleoside-binding site excludes uridine but supports beta-D-ribosylnicotinamide phosphorylation |
Homo sapiens |
? |
- |
? |
| 2.7.1.173 | more |
substrate specificity of recombinant Nrk2, overview. Classification of Nrk2 as an ATP-specific nicotinic acid riboside, tiazofurin, and uridine kinase. Poor cytidine monophosphate-forming activity of the enzyme. Structural basis of substrate specificity, overview |
Homo sapiens |
? |
- |
? |
| 2.7.1.173 | more |
the main NRK activity in human OVCAR-3 cells is due to the expression of enzyme NRK1 |
Homo sapiens |
? |
- |
? |
| 2.7.1.173 | more |
development of a highly sensitive, rapid and specific coupled enzymatic assay that allows simultaneous determination of NRK activitiy, as well as of nicotinic acid phosphoribosyltransferase, quinolinic acid phosphoribosyltransferase, and nicotinamide phosphoribosyltransferase activities, in various biological samples of various origins, evaluation and optimization using liver extracts, overview |
Homo sapiens |
? |
- |
? |
