EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
  2.6.1.70 | L-tryptophan + 3-phenylpyruvate |
40% activity with respect to aspartate |
Pseudomonas putida |
3-indole-2-oxopropanoate + L-phenylalanine |
- |
? |
| 2.6.1.70 | L-tryptophan + oxaloacetate |
reverse reaction, 77% activity with respect to L-phenylalanine |
Pseudomonas putida |
3-indole-2-oxopropanoate + L-aspartate |
- |
r |
| 2.6.1.70 | more |
cysteine, glutamine, arginine, alanine, threonine, L-aspartate dibutylester, L-phenylglycine, isoleucine, valine, serine, lysine, ketobutyrate, alpha-keto-beta-n-valerate, beta-hydroxypyruvate, prephenate are inert as substrates |
Pseudomonas putida |
? |
- |
? |
| 2.6.1.70 | more |
D amino acids are not utilized as substrates |
Pseudomonas putida |
? |
- |
? |
| 2.6.1.70 | more |
modification of the carboxyl group of L-phenylalanine exhibits great influence on the enzyme substrate interaction as do substituents at C-2 or shortening the side chain |
Pseudomonas putida |
? |
- |
? |
| 2.6.1.70 | more |
aspartate derivatives are used only with low activity if a modification at the position of the beta carbon is made |
Pseudomonas putida |
? |
- |
? |
| 2.6.1.70 | more |
addition of substituents in the aromatic ring in the para position decreases the affinity of the derivative to the enzyme apparently with increasing bulk of the group, for a given halogen, position at the aromatic ring has only marginal influence on the reaction rate |
Pseudomonas putida |
? |
- |
? |
| 2.6.1.70 | oxaloacetate + L-histidine |
reverse reaction, 4% activity with respect to L-phenylalanine |
Pseudomonas putida |
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-aspartate |
- |
r |
| 2.6.1.70 | oxaloacetate + L-tyrosine |
reverse reaction, 38% activity with respect to L-phenylalanine |
Pseudomonas putida |
p-hydroxyphenylpyruvate + L-aspartate |
- |
r |
| 2.6.1.70 | p-hydroxyphenylpyruvate + L-aspartate |
54% activity with respect to L-phenylpyruvate |
Pseudomonas putida |
oxaloacetate + L-tyrosine |
- |
? |
