EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   1.14.19.39 | more |
the enzyme is able to desaturate C16 and C18 fatty acids. When recombinantly expressed in yeast cells, the enzyme can also catalyze DELTA15 desaturation. The recombinant enzyme can also produce C14:2DELTA9,12, C15:2DELTA9,12, C17:2DELTA9,12, and C18:4DELTA6,9,12,15 when C14:1DELTA9, C15:1DELTA9, C17:1DELTA9, and C18:3DELTA6,9,12 substrates are available in yeast cells, product mass spectrometry analysis |
Caenorhabditis elegans |
? |
- |
? |
| 1.14.19.39 | oleate + AH2 + O2 |
oxygenation at the sn-2 position |
Acanthamoeba castellanii |
linoleate + A + 2 H2O |
- |
? |
| 1.14.19.39 | oleate + AH2 + O2 |
recombinant enzyme |
Caenorhabditis elegans |
linoleic acid + linolenic acid + A + 2 H2O |
- |
? |
| 1.14.19.39 | oleate + reduced acceptor + O2 |
enzyme is equally efficient with linoleate and oleate, via intermediates 9(Z),12(E)-octadecadienoate and 9,12(Z)-octadecadienoate, only the latter of which is further catalysed to give crepenynate, i.e. 9(Z)-octadecen-12-ynoate |
Crepis alpina |
crepenynate + acceptor + H2O |
product enantiomers in a ration of 3:1 |
? |
| 1.14.19.39 | palmitoleic acid + O2 |
recombinant enzyme |
Caenorhabditis elegans |
hexadecadienoic acid + hexadecatrienoic acid + A + 2 H2O |
- |
? |
| 1.14.19.39 | palmitoleoate + AH2 + O2 |
via intermediate DELTA9,12 hexadecadienoate |
Acanthamoeba castellanii |
9,12,15-hexadecatrienoate + A + H2O |
the product is n-1 polyunsaturated |
? |
| 1.14.19.39 | phosphatidylcholine + AH2 + O2 |
- |
Acanthamoeba castellanii |
? |
- |
? |
| 1.14.19.39 | phosphatidylcholine + reduced cytochrome b5 + O2 |
with NADH |
Physcomitrium patens |
? + cytochrome b5 + 2 H2O |
- |
? |
