EC Number   |
Specific Activity Minimum [µmol/min/mg] |
Specific Activity Maximum [µmol/min/mg] |
Reference |
|---|
   3.4.21.68 | -999 |
- |
- |
29594, 29597 |
| 3.4.21.68 | -999 |
- |
a study in sporadic Alzheimer's disease and age-matched control brain tissues reveals that the tPA proteolytic activity is negatively correlated to amyloid-beta peptide levels |
683922 |
| 3.4.21.68 | -999 |
- |
cerebral tPA activity is decreased during ageing in normal mice and this effect is worsened in mice overproducing amyloid-beta peptide assemblies. These phenomena result from a decrease in tPA expression and from an increase in the production of one of the tPA inhibitors, the plasminogen activator inhibitor type 1 (PAI-1) |
683922 |
| 3.4.21.68 | -999 |
- |
specific activity of 240000 I.U./mg protein |
649779 |
| 3.4.21.68 | -999 |
- |
the plasminogen activator inhibitor-1 antigen and its activity and their ratios to tissue-type plasminogen activator are all paradoxically lower with advancing age in patients with type 2 diabetes mellitus, t-PA is significantly and directly associated with increasing age |
707027 |
| 3.4.21.68 | -999 |
- |
tPA and PAI-1 activities in neural cells, overview |
718168 |
| 3.4.21.68 | 0.297 |
- |
- |
29587 |
| 3.4.21.68 | 7.4 |
- |
purified recombinant truncated enzyme, pH 8.3, 37°C |
717411 |
