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EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49-999 - Esp1 contributes to mitotic exit kinetics mainly through cohesin cleavage. Absence of Esp1 activity: only a minor mitotic exit delay observed which is consistent with a Cdc14 early anaphase release defect. Esp1 overexpression drives mitotic exit in Cdc20-depleted cells arrested in metaphase. Activity of overexpressed Esp1 depends on spindle integrity and the mitotic exit network. 700098
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.49-999 - The protease activity of Esp1 is required for anaphase spindle elongation in Mcd1-depleted cells (Mcd1 is a subunit of cohesin) 698119
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