EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
granulosa cell |
- |
763193 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
granulosa cell |
preovulatory follicular |
389373 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
granulosa cell |
- |
700178 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
granulosa cell |
cortisol oxidation increases threefold with antral follicle diameter, accompanied by threefold increase in 11beta-hydroxysteroid dehydrogenase activity. Neither intact cells nor homogenates display net 11-ketosteroid reductase activities. Intact granulosa cells from ovarian cysts exhibit significantly lower enzyme activities than cells from large antral follicles |
695089 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
granulosa cell |
- |
669908 |
1.1.1.188 | prostaglandin-F synthase |
granulosa cell |
both activities of enzymes AKR1C1/AKR1C2 and AKR1C3 are present in the periovuatory granulosa cell |
-, 690009 |
1.1.1.188 | prostaglandin-F synthase |
granulosa cell |
both activities of enzymes AKR1C1/AKR1C2 and AKR1C3 are present in the periovuatory granulosa cell. Prostaglandin F synthase mRNA and protein levels are low before treatment with gonadotropin and peak 24-36 h after gonadotropin administration |
-, 690009 |
1.1.1.53 | 3alpha(or 20beta)-hydroxysteroid dehydrogenase |
granulosa cell |
- |
287104 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
granulosa cell |
- |
700178 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
granulosa cell |
luteinizing granulosa cell |
693380 |
1.14.11.53 | mRNA N6-methyladenine demethylase |
granulosa cell |
of ovaries, N6-methyladenosine increases in granulosa cells of human aged ovaries , while FTO-knockdown granulosa cells show faster aging-related phenotypes |
764437 |
1.14.14.154 | sterol 14alpha-demethylase |
granulosa cell |
- |
659942 |
1.14.14.32 | 17alpha-hydroxyprogesterone deacetylase |
granulosa cell |
- |
738346 |
1.14.15.6 | cholesterol monooxygenase (side-chain-cleaving) |
granulosa cell |
pre-ovulatory follicle F1 |
706699 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
granulosa cell |
- |
659436 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
granulosa cell |
periovulatory granulosa cell |
697636 |
1.5.1.20 | methylenetetrahydrofolate reductase [NAD(P)H] |
granulosa cell |
- |
686829 |
1.6.3.5 | renalase |
granulosa cell |
substantial expression in granulosa |
728281 |
2.3.1.48 | histone acetyltransferase |
granulosa cell |
- |
756551 |
2.4.1.212 | hyaluronan synthase |
granulosa cell |
high isozyme content |
737218 |
2.4.2.26 | protein xylosyltransferase |
granulosa cell |
cell culture |
637621 |
2.7.1.36 | mevalonate kinase |
granulosa cell |
cultured cell |
692079 |
2.7.1.36 | mevalonate kinase |
granulosa cell |
cultured granulosa cell |
694182 |
2.7.11.30 | receptor protein serine/threonine kinase |
granulosa cell |
- |
666359 |
2.7.2.3 | phosphoglycerate kinase |
granulosa cell |
ovary |
701562 |
3.1.1.79 | hormone-sensitive lipase |
granulosa cell |
- |
693448 |
3.1.6.2 | steryl-sulfatase |
granulosa cell |
luteinized, follicle |
656370 |
3.1.6.2 | steryl-sulfatase |
granulosa cell |
primary cultures of granulosa cells matured in vitro with follicle-stimulating hormone and testosterone |
656638 |
3.2.1.166 | heparanase |
granulosa cell |
induction of heparanase by luteinizing hormone |
692095 |
3.4.18.1 | cathepsin X |
granulosa cell |
in oocytes |
683378 |
3.4.21.107 | peptidase Do |
granulosa cell |
the luteinizing granulosa cells of the corpus luteum express the highest levels of Htra3 |
712615 |
3.4.21.109 | matriptase |
granulosa cell |
ovary |
698819 |
3.4.21.122 | transmembrane protease serine 2 |
granulosa cell |
TMPRSS2 protein is present, TMPRSS2 mRNA is not present |
764650 |
3.4.21.75 | Furin |
granulosa cell |
primary |
732716 |
3.4.21.79 | granzyme B |
granulosa cell |
- |
709759 |
3.4.22.56 | caspase-3 |
granulosa cell |
procaspase-3 level is elevated 2fold to 5fold in preovulatory, compared to prehierarchal follicle granulosa cells |
647633 |
3.4.22.60 | caspase-7 |
granulosa cell |
- |
668416 |
3.4.23.B1 | napsin |
granulosa cell |
- |
754263 |
3.4.24.35 | gelatinase B |
granulosa cell |
- |
-, 708893, 733456 |
3.4.24.79 | pappalysin-1 |
granulosa cell |
enzyme expression during follicular development and in cell culture |
683873 |
3.4.24.86 | ADAM 17 endopeptidase |
granulosa cell |
granulosa cells of bovine preovulatory follicles |
754733 |
3.4.24.B11 | ADAMTS1 endopeptidase |
granulosa cell |
- |
713020, 733733 |
3.5.1.92 | pantetheine hydrolase |
granulosa cell |
regulation of VNN2 transcripts in bovine follicles prior to ovulation, high levels of gonadotropins regulate VNN2 mRNA expression in granulosa cells of bovine preovulatory follicles |
-, 733455 |
4.6.1.1 | adenylate cyclase |
granulosa cell |
AC isoforms 3, 4, 6, 8, and 9 |
682037 |
5.3.99.3 | prostaglandin-E synthase |
granulosa cell |
both microsomal enzyme immunostaining and mRNA, enzyme is induced by equine and human chorionic gonadotropin treatment |
681103 |
5.3.99.3 | prostaglandin-E synthase |
granulosa cell |
low level of cPGES |
668886 |
5.3.99.3 | prostaglandin-E synthase |
granulosa cell |
low level of mPGES-2 |
668886 |
5.3.99.3 | prostaglandin-E synthase |
granulosa cell |
mPGES-1 |
668886 |