EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.205 | IMP dehydrogenase |
HL-60 cell |
leukemic cell line |
347916 |
1.1.1.37 | malate dehydrogenase |
HL-60 cell |
- |
762064 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
HL-60 cell |
- |
671713 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
HL-60 cell |
treatment with docosahexaenoic acid results in 60% decrease in GPx-4 level |
688924 |
1.11.1.6 | catalase |
HL-60 cell |
- |
699926 |
1.11.1.9 | glutathione peroxidase |
HL-60 cell |
- |
688924 |
1.11.2.2 | myeloperoxidase |
HL-60 cell |
- |
697307, 713436, 742569, 764118, 765381 |
1.13.11.34 | arachidonate 5-lipoxygenase |
HL-60 cell |
- |
690170, 711301 |
1.13.11.34 | arachidonate 5-lipoxygenase |
HL-60 cell |
the 5-lipoxygenase core promoter is unmethylated, expression of 5-lipoxygenase protein upon differentiation |
704997 |
1.14.11.53 | mRNA N6-methyladenine demethylase |
HL-60 cell |
- |
763823 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
HL-60 cell |
during the differentiation of leukemic HL60 cells, the decreased hTERT expression is accompanied by the LSD1 recruitment to the hTERT promoter |
755188 |
1.14.11.66 | [histone H3]-trimethyl-L-lysine9 demethylase |
HL-60 cell |
- |
744722 |
1.14.11.68 | [histone H3]-trimethyl-L-lysine27 demethylase |
HL-60 cell |
- |
753742 |
1.14.11.69 | [histone H3]-trimethyl-L-lysine36 demethylase |
HL-60 cell |
- |
744722 |
1.14.11.B19 | [histone H3]-trimethyl-L-lysine56 demethylase |
HL-60 cell |
low expression level |
755194 |
1.14.14.94 | leukotriene-B4 20-monooxygenase |
HL-60 cell |
induction of in all-trans-retinoic acid-treated HL60 cells |
657762 |
1.14.14.94 | leukotriene-B4 20-monooxygenase |
HL-60 cell |
promyelocytic leukemic cell line |
703413 |
1.14.19.20 | DELTA7-sterol 5(6)-desaturase |
HL-60 cell |
- |
682873 |
1.14.99.38 | cholesterol 25-monooxygenase |
HL-60 cell |
- |
746440 |
1.14.99.66 | [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase |
HL-60 cell |
during the differentiation of leukemic HL60 cells, the decreased hTERT expression is accompanied by the LSD1 recruitment to the hTERT promoter |
755188 |
1.17.4.1 | ribonucleoside-diphosphate reductase |
HL-60 cell |
- |
744504, 744958 |
1.17.4.1 | ribonucleoside-diphosphate reductase |
HL-60 cell |
a promyelocytic leukemia cell line |
688283 |
1.17.4.1 | ribonucleoside-diphosphate reductase |
HL-60 cell |
promyelocytic leukemia cell |
726918 |
1.17.4.2 | ribonucleoside-triphosphate reductase (thioredoxin) |
HL-60 cell |
- |
687180 |
1.17.4.2 | ribonucleoside-triphosphate reductase (thioredoxin) |
HL-60 cell |
promyelocytic leukemia cells |
672890 |
1.3.1.21 | 7-dehydrocholesterol reductase |
HL-60 cell |
- |
725672 |
1.3.1.72 | DELTA24-sterol reductase |
HL-60 cell |
- |
682873, 764619 |
1.3.1.72 | DELTA24-sterol reductase |
HL-60 cell |
promyelocytic cells |
654502 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
HL-60 cell |
2.3% of the activity in liver |
655483 |
1.6.2.4 | NADPH-hemoprotein reductase |
HL-60 cell |
- |
743141, 743656 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
HL-60 cell |
- |
685998, 711166, 763912 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
HL-60 cell |
bilirubin concentration-dependently reduces NADPH oxidase-dependent superoxide production stimulated by phorbol 12-myristate 13-acetate |
687050 |
1.6.5.2 | NAD(P)H dehydrogenase (quinone) |
HL-60 cell |
- |
745830 |
1.7.1.7 | GMP reductase |
HL-60 cell |
- |
659550 |
1.8.1.7 | glutathione-disulfide reductase |
HL-60 cell |
doxorubicin-insensitive leukemic cell line HL-60-R, a subclone of HL-60 |
657878 |
1.8.1.9 | thioredoxin-disulfide reductase |
HL-60 cell |
- |
688735 |
2.1.1.13 | methionine synthase |
HL-60 cell |
- |
684467, 733653 |
2.1.1.137 | arsenite methyltransferase |
HL-60 cell |
- |
718748, 733451 |
2.1.1.319 | type I protein arginine methyltransferase |
HL-60 cell |
- |
756861 |
2.1.1.355 | [histone H3]-lysine9 N-trimethyltransferase |
HL-60 cell |
interaction between growth factor independent 1 and G9a in vivo |
675958 |
2.1.1.6 | catechol O-methyltransferase |
HL-60 cell |
- |
657534 |
2.1.1.72 | site-specific DNA-methyltransferase (adenine-specific) |
HL-60 cell |
- |
719373 |
2.3.1.125 | 1-alkyl-2-acetylglycerol O-acyltransferase |
HL-60 cell |
- |
486246 |
2.3.1.149 | Platelet-activating factor acetyltransferase |
HL-60 cell |
- |
16279 |
2.3.1.20 | diacylglycerol O-acyltransferase |
HL-60 cell |
leukemia, HL-60 cell line |
486246 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
HL-60 cell |
differentiated |
487375 |
2.3.1.85 | fatty-acid synthase system |
HL-60 cell |
- |
720118 |
2.4.1.143 | alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase |
HL-60 cell |
- |
658123 |
2.4.1.144 | beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
HL-60 cell |
- |
658123 |
2.4.1.150 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase |
HL-60 cell |
C2GnT, promyelocytic leukaemia HL-60 cells |
638564 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
HL-60 cell |
- |
639528 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
HL-60 cell |
- |
658123 |
2.4.1.206 | lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase |
HL-60 cell |
- |
704447 |
2.4.1.80 | ceramide glucosyltransferase |
HL-60 cell |
- |
489417, 691791 |
2.4.2.1 | purine-nucleoside phosphorylase |
HL-60 cell |
- |
703162 |
2.4.2.31 | NAD+-protein-arginine ADP-ribosyltransferase |
HL-60 cell |
- |
723565 |
2.4.2.8 | hypoxanthine phosphoribosyltransferase |
HL-60 cell |
myeloid leukemic cell line |
672965 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
HL-60 cell |
- |
764812 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
HL-60 cell |
- |
657703 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
HL-60 cell |
phorbol myristate actetate-stimulated |
658140 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
HL-60 cell |
the cAMP responsive element binding protein binding site of the hST3Gal V promoter plays a critical role in transcriptional regulation of the hST3Gal V gene during HL-60 cell differentiation |
658723 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
HL-60 cell |
type 2 isozyme |
672358 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
HL-60 cell |
upregulation of GM3 synthase through protein kinase C/extracellular regulated kinases-dependent cAMP-responsive element binding protein activation results in the differentiation of HL-60 cells by inducing expression of CD11b |
658853 |
2.5.1.18 | glutathione transferase |
HL-60 cell |
- |
687298, 703157, 705056 |
2.5.1.39 | 4-hydroxybenzoate polyprenyltransferase |
HL-60 cell |
- |
671299 |
2.5.1.49 | O-acetylhomoserine aminocarboxypropyltransferase |
HL-60 cell |
- |
684467 |
2.5.1.6 | methionine adenosyltransferase |
HL-60 cell |
leukemia promyelotic cells |
657534 |
2.7.1.107 | diacylglycerol kinase (ATP) |
HL-60 cell |
level of DGKgamma is rapidly and markedly decreased upon cellular differentiation into macrophages |
640373 |
2.7.1.107 | diacylglycerol kinase (ATP) |
HL-60 cell |
levels of DGKgamma mRNA/protein is rapidly and markedly decreased upon cellular differentiation into macrophages |
640373 |
2.7.1.113 | deoxyguanosine kinase |
HL-60 cell |
- |
671801 |
2.7.1.113 | deoxyguanosine kinase |
HL-60 cell |
3fold increase when cells start to proliferate |
671801 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
HL-60 cell |
non-differentiated promyelocytic-leukaemia cell line, InsP3 3-kinase B mRNA |
640751 |
2.7.1.138 | ceramide kinase |
HL-60 cell |
- |
691938 |
2.7.1.138 | ceramide kinase |
HL-60 cell |
CerK mRNA expression and activity decreased during macrophagelike cell differentiation of HL-60 cells |
692594 |
2.7.1.20 | adenosine kinase |
HL-60 cell |
- |
722914 |
2.7.1.60 | N-acylmannosamine kinase |
HL-60 cell |
- |
641741 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
HL-60 cell |
- |
693300, 738199 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
HL-60 cell |
enzyme is enriched in the uropod during chemotaxis of differentiated HL-60 cells. Enrichment occurs early upon chemoattractant stimulation and is persistent during chemotaxis, concomitant with enrichment of phosphatidylinositol 4,5-bisphosphate |
694079 |
2.7.1.74 | deoxycytidine kinase |
HL-60 cell |
- |
662521, 721969, 761020 |
2.7.1.91 | sphingosine kinase |
HL-60 cell |
- |
704087 |
2.7.10.2 | non-specific protein-tyrosine kinase |
HL-60 cell |
macrophage-like differentiated |
672781 |
2.7.10.2 | non-specific protein-tyrosine kinase |
HL-60 cell |
promyelotic leukemia cell line |
662838 |
2.7.11.1 | non-specific serine/threonine protein kinase |
HL-60 cell |
- |
723080 |
2.7.11.10 | IkappaB kinase |
HL-60 cell |
- |
722690, 722826 |
2.7.11.13 | protein kinase C |
HL-60 cell |
- |
491032 |
2.7.11.15 | beta-adrenergic-receptor kinase |
HL-60 cell |
- |
677232 |
2.7.11.15 | beta-adrenergic-receptor kinase |
HL-60 cell |
high expression of beta-ARK 1 |
490989 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
HL-60 cell |
- |
691612 |
2.7.11.30 | receptor protein serine/threonine kinase |
HL-60 cell |
a myeloid leukemic cell line |
691532 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
HL-60 cell |
- |
693328 |
2.7.12.2 | mitogen-activated protein kinase kinase |
HL-60 cell |
- |
679032, 740713 |
2.7.4.21 | inositol-hexakisphosphate 5-kinase |
HL-60 cell |
- |
662355 |
2.7.7.19 | polynucleotide adenylyltransferase |
HL-60 cell |
- |
761995 |
2.7.7.49 | RNA-directed DNA polymerase |
HL-60 cell |
- |
693312 |
2.7.7.96 | ADP-D-ribose pyrophosphorylase |
HL-60 cell |
- |
761999 |
2.7.8.27 | sphingomyelin synthase |
HL-60 cell |
- |
722907, 723525 |
3.1.1.47 | 1-alkyl-2-acetylglycerophosphocholine esterase |
HL-60 cell |
- |
650326 |
3.1.1.77 | acyloxyacyl hydrolase |
HL-60 cell |
- |
246545, 246546, 246547, 246548, 246549, 246550 |
3.1.2.4 | 3-hydroxyisobutyryl-CoA hydrolase |
HL-60 cell |
promyelocytic leukemia cell line |
665823 |
3.1.22.1 | deoxyribonuclease II |
HL-60 cell |
- |
696131 |