EC Number   |
Source Tissue |
Reference  |
|---|
   3.4.22.49 | HeLa-S3 cell |
- |
638863 |
| 3.4.22.49 | HeLa cell |
- |
638865, 638869, 664551, 681015, 709217, 718320, 718433, 731689, 732669 |
| 3.4.22.49 | oocyte |
- |
664545, 664553, 664676, 682062, 682065 |
| 3.4.22.49 | granule cell |
- |
679433 |
| 3.4.22.49 | brain |
in a murine model of absent securin expression, the PTTG knock-out mouse, separase and Rad21 are over-expressed in multiple brain regions. Furthermore, Rad21 mRNA expression is highly correlated with that of securin, separase, cyclin C and sestrin 2 in fetal brains |
681037 |
| 3.4.22.49 | cerebral cortex |
highly expressed in human fetal cerebral cortex compared with adult |
681037 |
| 3.4.22.49 | non-small cell lung cancer cell line |
- |
697184 |
| 3.4.22.49 | breast cancer cell |
increased expression of separase |
697382 |
| 3.4.22.49 | colorectal cancer cell line |
separase expression is very high in both normal nonneoplastic and neoplastic colons |
697382 |
| 3.4.22.49 | osteosarcoma cell |
increased expression of separase |
697382 |
