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EC Number
Source Tissue
Commentary
Reference
3.4.22.49
LAMA-84 cell
-
732703
3.4.22.49
mammary epithelial cell line
diploid FSK3 mouse mammary epithelial cells
700945
3.4.22.49
MDA-MB-231 cell
-
718433
3.4.22.49
meiotic cell
-
710317
3.4.22.49
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human separase is present in cells as a part of very large protein complex, which in addition to securin contains also Cdk and cyclin B1, both able to inhibit separase
718194
3.4.22.49
non-small cell lung cancer cell line
-
697184
3.4.22.49
oocyte
-
664545
,
664553
,
664676
,
682062
,
682065
3.4.22.49
osteosarcoma cell
increased expression of separase
697382
3.4.22.49
prostate cancer cell line
increased expression of separase
697382
3.4.22.49
prostate gland cancer cell
overexpressed in numerous human cancers including breast, bone, brain, and prostate
752903
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