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EC Number	Source Tissue	Commentary	Reference
3.4.22.43	pharynx	-	707906
3.4.22.43	RKO cell	-	732591
3.4.22.43	SK-N-MC cell	-	732049
3.4.22.43	skin	-	669460, 707906
3.4.22.43	skin	CTSV is highly expressed across the entire epidermis in normal skin. But CTSV expression levels are lower in the basal layer than those in the stratum corneum side in the hyperpigmented region	752678
3.4.22.43	stomach	-	707906
3.4.22.43	stratum corneum	-	669460
3.4.22.43	stratum corneum	in extracellular space associated to corneodesmosomes, co-localization of the enzyme and inhibitor cystatin M/E	669754
3.4.22.43	stratum granulosum	-	709405
3.4.22.43	stratum granulosum	co-localization of the enzyme and inhibitor cystatin M/E, which are separately transported within lamellar granules	669754

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Release 2023.1 (January 2023)