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EC Number Renatured (Commentary) Reference
Display the reaction diagram Show all sequences 2.7.7.89the enzyme can be reconstituted from two purified polypeptides that comprise the N-terminal two-thirds of the protein and the C-terminal one-third of the protein. The reconstituted enzyme exhibits normal activation by signal transduction proteon PII. Properties of the reconstituted enzyme are consistent with the protein activators PII and PII-UMP binding to the enzyme domain with the opposing activity, with intramolecular signal transduction by direct interactions between the N-terminal adenylyl-removing catalytic domain and the C-terminal adenylyltransferase catalytic domain 702300
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