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EC Number General Information Commentary Reference
Show all pathways known for 6.3.4.21Display the word mapDisplay the reaction diagram Show all sequences 6.3.4.21physiological function both NAPRT and nicotinamide phosphoribosyltransferase NAMPT increase intracellular NAD+ levels. NAPRT silencing reduces energy status, protein synthesis, and cell size in ovarian and pancreatic cancer cells. NAPRT silencing sensitizes cells to NAMPT inhibitors both in vitro and in vivo 744621
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