EC Number   |
General Information |
Reference |
|---|
   6.3.2.36 | malfunction |
the deletion mutant strain grows well in media supplemented with 1 mM CoA. The deletion mutant strain can not grow at all in the absence of CoA |
704547 |
| 6.3.2.36 | metabolism |
the common pathway for coenzyme A biosynthesis which involves two enzymes to convert pantoate to 4'-phosphopantothenate involves two enzymes, pantoate kinase, and phosphopantothenate synthetase (PPS), they are responsible for this conversion in archaea. In archea, In these archaea, pantoate is phosphorylated by PoK to produce 4-phosphopantoate (PPo), and then condensation of PPo and beta-alanine is catalyzed by PPS, generating 4'-phosphopantothenate |
-, 746403 |
| 6.3.2.36 | more |
enzyme structure and substrate binding analysis, structure comparisons, structure-function analysis, overview |
-, 746403 |
| 6.3.2.36 | physiological function |
enzyme PPS catalyzes the ATP-dependent condensation of 4-phosphopantoate and beta-alanine generating 4'-phosphopantothenate |
-, 746403 |
