EC Number   |
General Information |
Reference |
|---|
    6.3.2.13 | evolution |
the DNPR motif that is characteristic of meso-diaminopimelate-adding enzymes is replaced by HDNR |
744440 |
| 6.3.2.13 | more |
MurE substrate binding sitestructures and three-dimensional structure modeling by homology modeling method, structure comparisons of Mur ligases, detailed overview. Identification of residues playing an important role in the catalytic activity of each of the Mur enzymes, docking of enzyme and substrate and ATP |
715975 |
| 6.3.2.13 | more |
protein-protein interaction network of MurC, D, E, and F synthetases, overview |
-, 728598 |
| 6.3.2.13 | more |
the HDNR motif plays a role in the interaction of the enzyme with L-alanine and meso-diaminopimelic acid. ENzyme structure homology modeling |
744440 |
| 6.3.2.13 | physiological function |
ATP-dependent Mur ligases play essential roles in the biosynthesis of cell wall peptidoglycan as they catalyze the ligation of key amino acid residues to the stem peptide at the expense of ATP hydrolysis |
-, 728598 |
