EC Number |
General Information |
Reference |
---|
6.2.1.30 | physiological function |
in a mutant lacking a 6-phophogluconate dehydratase and therefore unable to produce 2-keto-3-deoxy-6-phosphogluconate, phenylacetyl-CoA ligase activity is high, even in the presence of glucose plus phenylacetic acid. In wild-type, phenylacetyl-CoA ligase activity is low under these conditions |
-, 705560 |
6.2.1.30 | metabolism |
PCL is essentially involved in the pathway of penicillin biosynthesis, overview. Conditions that lead to peroxisome proliferation but simultaneously interfere with the normal physiology of the cell may be detrimental to antibiotic production |
-, 713830 |
6.2.1.30 | more |
conditions that lead to peroxisome proliferation but simultaneously interfere with the normal physiology of the cell may be detrimental for antibiotic production |
-, 713830 |
6.2.1.30 | more |
conditions that lead to peroxisome proliferation but simultaneously interfere with the normal physiology of the cell may be detrimental for antibiotic production. The number of peroxisomes in a dnm1 overexpression strain variant is enhanced relative to those of wild-type controls |
-, 713830 |
6.2.1.30 | physiological function |
PCL is a side-chain precursor activation enzyme essentially involved in the pathway of penicillin biosynthesis, overview |
-, 713830 |
6.2.1.30 | metabolism |
the enzyme catalyzes the second last step in penicillin N biosynthesis in microbodies, pathway overview and interorganelle intermediate transport |
716117 |
6.2.1.30 | more |
insertional mutagenesis of paaK1, which encodes phenylacetate-CoA ligase, does not result in a phenylacetate-conditional growth probably due to the presence of a putative paralogue gene paaK2 |
-, 727575 |
6.2.1.30 | more |
insertional mutagenesis of paaK1, which encodes phenylacetate-CoA ligase, does not result in a phenylacetate-conditional growth probably due to the presence of a putative paralogue gene paaK2. The paaK1 deletion mutant IAI1 does not show any growth-defective phenotype in phenylacetate |
-, 727575 |
6.2.1.30 | physiological function |
isozyme PaaK1 does not play a distinct role in pathogenesis of Burkholderia cenocepacia in Caenorhabditis elegans, although the catabolic pathway for phenylacetic acid degradation is a requirement for full pathogenesis |
-, 727575 |
6.2.1.30 | evolution |
PaaK1 and PaaK2 form a unique subgroup within the adenylate-forming enzyme superfamily |
-, 727874 |