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EC Number General Information Commentary Reference
Show all pathways known for 6.1.1.12Display the word mapDisplay the reaction diagram Show all sequences 6.1.1.12malfunction LBSL, i.e. leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation, is a monogenic disease associated with a large variety of mutations affecting the human nuclear gene DARS2, encoding mt-AspRS, overview 714091
Show all pathways known for 6.1.1.12Display the word mapDisplay the reaction diagram Show all sequences 6.1.1.12physiological function the enzyme induces an anti-inflammatory effect in mice with T-cell transfer colitis by interacting with interleukin-8 receptors 727335
Show all pathways known for 6.1.1.12Display the word mapDisplay the reaction diagram Show all sequences 6.1.1.12physiological function the mitochondrial aspartyl-tRNA synthetase is a key enzyme for mitochondrial translation and is correlated with leukoencephalopathy 714091
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