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Results 1 - 6 of 6
EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 5.4.2.6malfunction deletion of pgmB affects known virulence factors of Streptococcus mutans, specifically acid tolerance, mutant strain MU1593 is defective in its acid-responsiveness. The DELTApgmB strain shows a decreased ability to survive acid challenge. Additionally, the strain lacking beta-phosphoglucomutase has a diminished glycolytic profile compared with the parental strain. Proton permeability is increased in strain MU1593. Deletion of pgmB has a negative impact on the virulence of Streptococcus mutans in the Galleria mellonella (greater wax worm) animal model. Phenotype of strain MU1593, overview -, 728265
Display the word mapDisplay the reaction diagram Show all sequences 5.4.2.6more fluoromagnesate and fluoroaluminate complexes of beta-phosphoglucomutase demonstrate the importance of charge balance in transition-state stabilization for phosphoryl transfer enzymes, overview 728684
Display the word mapDisplay the reaction diagram Show all sequences 5.4.2.6more reaction mechanism analysis by docking techniques and QM/MM theoretical method, overview. Residues Ser114 and Lys145 and Mg2+ play important roles in stabilizing the large negative charge on the phosphate through strong coordination with the phosphate oxygens and guiding the phosphate group throughout the catalytic process 728173
Display the word mapDisplay the reaction diagram Show all sequences 5.4.2.6physiological function the enzyme is involved in conversion of kojibiose into beta-D-glucose 6-phosphate, a substrate of the glycolytic pathway. Disaccharide utilization pathway via phosphorolysis in hyperthermophilic archaea -, 725294
Display the word mapDisplay the reaction diagram Show all sequences 5.4.2.6physiological function the enzyme is involved in the kojibiose catabolic pathway -, 725294
Display the word mapDisplay the reaction diagram Show all sequences 5.4.2.6physiological function The enzyme plays a role at the juncture of carbohydrate metabolism and virulence. beta-Phosphoglucomutase contributes to aciduricity in Streptococcus mutans -, 728265
Results 1 - 6 of 6