EC Number   |
General Information |
Reference |
|---|
    5.4.2.11 | malfunction |
enzyme knockdown significantly inhibits glioma cell proliferation, promotes glioma cell apoptosis, induces S phase cell cycle arrest and inhibits glioma cell migration and invasion in vitro |
748795 |
| 5.4.2.11 | metabolism |
anaerobic fermentative metabolism of glycerol. Proteome analysis as well as enzyme assays performed in cell-free extracts demonstrate that glycerol is degraded via glyceraldehyde-3-phosphate, which is further metabolized through the lower part of glycolysis leading to formation of mainly ethanol and hydrogen |
748573 |
| 5.4.2.11 | metabolism |
the enzyme catalyzes the interconversion of 3-phosphoglycerate and 2-phosphoglycerate as a key step in the glycolytic pathway |
-, 726607 |
| 5.4.2.11 | more |
active site residues are Thr21, Gly22, Tyr90, Lys98, Arg114 and Arg115 |
-, 726607 |
| 5.4.2.11 | physiological function |
Brucellae are intracellular bacterial pathogens that cause Brucellosis. Earlier immune response plays an important role in the Brucella infection. The phosphoglyceromutase protein could induce Th1 and Th2-type immune responses in vivo and in vitro |
-, 746555 |
| 5.4.2.11 | physiological function |
the enzyme is associated with the grade of glioma and is involved in the biological behavior of glioma cells |
748795 |
