EC Number   |
General Information |
Reference |
|---|
   4.3.3.2 | evolution |
strictosidine synthases belong to the beta-propeller fold family characterized by an all-beta architecture with four to eight blades, each consisting of four antiparallel beta-sheets, arranged around a pseudo symmetry axis |
729396 |
| 4.3.3.2 | malfunction |
knockout of OsSTRL2 in rice causes male sterility |
749356 |
| 4.3.3.2 | metabolism |
the enzyme is involved in biosynthesis of 3-alpha(S)-strictosidine, a glycosylated indole alkaloid and central precursor of the entire monoterpenoid indole alkaloid biosynthesis, from tryptamine and secologanin and of dolichantoside from N-omega-methyltryptamine and secologanin |
729484 |
| 4.3.3.2 | metabolism |
the enzyme is involved in terpenoid indole alkaloid biosynthetic pathway |
743812 |
| 4.3.3.2 | more |
the six bladed beta-propeller protein has two regions which cover the enzyme active site. The observed activity changes suggest important roles of both regions in protein folding, stability and catalysis |
729396 |
| 4.3.3.2 | more |
transgenic Catharantus roseus cultures over-expressing tryptophan decarboxylase and/or strictosidine synthase do not produce higher levels of terpenoid indole alkaloids as compared with the non-transformed control cells |
730920 |
| 4.3.3.2 | physiological function |
involved in biosynthesis of monoterpenoid indole alkaloids |
703154 |
| 4.3.3.2 | physiological function |
strictosidine synthases catalyze the formation of strictosidine, a key intermediate in the biosynthesis of a large variety of monoterpenoid indole alkaloids |
729396 |
| 4.3.3.2 | physiological function |
the enzyme is involved in biosynthesis of 3-alpha(S)-strictosidine, a glycosylated indole alkaloid and central precursor of the entire monoterpenoid indole alkaloid biosynthesis, from tryptamine and secologanin and of dolichantoside from N-omega-methyltryptamine and secologanin. Alkaloid production is associated to the antioxidant response induced under oxidative stress |
729484 |
| 4.3.3.2 | physiological function |
the enzyme plays key roles in anther development and pollen wall formation in rice |
749356 |
