EC Number   |
General Information |
Reference |
|---|
    4.2.1.51 | evolution |
all plant clades include PAC domain-containing arogenate dehydratases, suggesting that the prephenate dehydratase activity, and thus the ability to synthesize L-phenylalanine using phenylpyruvate as an intermediate, has been preserved throughout the evolution of plants. This pathway together with the arogenate pathway gives plants a broad and versatile capacity to synthesize L-phenylalanine and its derived compounds |
748952 |
| 4.2.1.51 | malfunction |
use of a T326P mutation in the regulation domain of pheA (pheAfbr) for L-phenylalanine production. Overexpression of pheAfbr and/or wild-type aroF is helpful for the enhancement of the key enzymes in L-phenylalanine biosynthesis |
-, 702720 |
| 4.2.1.51 | metabolism |
prephenate dehydratase takes part in the biosynthetic pathway of flavan-3-ols, overview |
714881 |
| 4.2.1.51 | metabolism |
the enzyme is involved in aromatic amino acid biosynthesis |
692260 |
| 4.2.1.51 | metabolism |
the enzyme is involved in L-phenylalanine biosynthesis pathway |
747338 |
| 4.2.1.51 | metabolism |
the enzyme is involved in the phenylpyruvate biosynthetic pathway |
748952 |
| 4.2.1.51 | metabolism |
transgenic Arabidopsis plants expressing a truncated, feedback-insensitive chorismate mutase/prephenate dehydratase gene accumulate Phe (up to 100fold compared to control plants) and are more sensitive than wild-type plants to the Trp biosynthesis inhibitor 5-methyl-Trp. Thus Phe biosynthesis competes with Trp biosynthesis from their common precursor chorismate. A number of secondary metabolites derived from all three aromatic amino acids (Phe, Trp and Tyr) are altered in the transgenic plants, implying regulatory cross-interactions between the flux of aromatic amino acid biosynthesis from chorismate and their further metabolism into various secondary metabolites. Truncated PheA expression has a minimal effect on primary metabolism and on the Arabidopsis transcriptome. A high proportion of the feedback-insensitive chorismate mutase/prephenate dehydratase polypeptide produced by this transgene is translocated into the plastids |
706236 |
| 4.2.1.51 | more |
a decrease in catechins content, 2-phenylethanol, and PDT activity is observed in the tea shoots infested by Exobasidium vexans over healthy shoots. Drought stress induced by withholding water for a period of 8 days causes initial increase in the contents of the catechins and 2-phenylethanol, and in PDT activity, but decreases with 3 day onwards with an increase in the severity of water stress, detailed overview |
714881 |
| 4.2.1.51 | physiological function |
involved in aromatic amino acid metabolism |
706809 |
