EC Number |
General Information |
Reference |
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4.2.1.143 | malfunction |
conidiation phenotype and sclerotial phenotype of wild-type, enzyme deletion DELTAaflK, and complemented mutant DELTA aflK::aflK strains, overview. The aflK deletion-mutant DELTAaflK exhibits a significant decrease in sclerotial production and aflatoxin biosynthesis compared with wild-type and the complementation strain DELTAaflK::aflK. The mutation DELTAaflK does not affect the ability of Aspergillus flavus to infect seeds, but downregulates aflatoxin production after seed infection |
-, 748620 |
4.2.1.143 | metabolism |
genes aflD, aflK, aflQ, and aflR are involved in aflatoxin biosynthesis |
-, 748719 |
4.2.1.143 | physiological function |
enzyme catalyzes bisfuran ring closure in versiconal hemiacetal to form versicolorin B. This reaction is required for the subsequent activation to aflatoxin B1-8,9 epoxide, a highly reactive and toxic aflatoxin metabolite |
721453 |
4.2.1.143 | physiological function |
enzyme is involved in aflatoxin biosynthesis. A deletion mutant accumulates large amounts of 5'-oxoaverantin, 5'-hydroxyaverantin, averantin, (2'S,5'S)-averufin, and averufanin in the mycelium, leading to bright orange colour |
-, 721335 |
4.2.1.143 | physiological function |
the enzyme is encoded by gene alfK, which is part of the gene cluster involved in aflatoxin biosynthesis. Negative role of aflK in sclerotial production. Relationship between enzyme AflK and sclerotial production in Aspergillus flavus |
-, 748620 |