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EC Number General Information Commentary Reference
Show all pathways known for 4.1.1.45Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.45metabolism the enzyme plays a key role in NAD+ biosynthesis from tryptophan. The enzyme is associated with cholesterol metabolism 727425
Show all pathways known for 4.1.1.45Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.45physiological function ACMSD inhibition increases de novo NAD+ biosynthesis 748372
Show all pathways known for 4.1.1.45Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.45physiological function amino-beta-carboxymuconate-semialdehyde-decarboxylase limits quinolinic acid formation by competitive production of the neuroprotective metabolite picolinic acid. Decreased ACMSD activity can lead to excess quinolinic acid 749404
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