EC Number   |
General Information |
Reference |
|---|
   3.6.1.17 | malfunction |
loss of NDX-4 leads to upregulation of key stress responsive genes that likely compensate for the in vivo role of NDX-4 in protection against deleterious consequences of oxidative stress. NDX-4 deficiency protects nematodes from acute heat shock |
-, 719339 |
| 3.6.1.17 | physiological function |
Ap4A-hydrolase is involved in regulation of cell proliferation, DNA replication, RNA processing, apoptosis and DNA repair. SARS coronavirus protein 7a interacts with human Ap4A-hydrolase in the cytoplasm |
713580 |
| 3.6.1.17 | physiological function |
the enzyme contributes to genomic stability in vivo in Caenorhabditis elegans |
-, 719339 |
| 3.6.1.17 | physiological function |
the primary and secondary waves of platelet aggregation and dense granule release are strongly induced by nanomolar ENPP4 in the presence of Ap3A, while Ap3A alone initiates a primary wave of aggregation followed by rapid disaggregation. ENPP4 mediates platelet aggregation via release of ADP from Ap3A and activation of ADP receptors |
733563 |
