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EC Number General Information Commentary Reference
Show all pathways known for 3.5.4.12Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.12malfunction DELTA(DCD) protein in the alr mutant (albinic leaf and growth retardation) is a loss-of-function protein that lacks binding ability. Deoxycytidine monophosphate deaminase deficiency causes accumulation of DNA damage in the alr mutant, sometimes leading to cell apoptosis. Deoxycytidine monophosphate deaminase deficiency triggers cell cycle checkpoints and arrests cell progression at the G1/S-phase. Decreased cell proliferation and defective chloroplast development in the alr mutant is demonstrated. The expression of nuclear and plastid genome replication genes is down-regulated under decreased dTTP 757330
Show all pathways known for 3.5.4.12Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.12metabolism dCMPD is pivotal in deoxyuridine analogs nucleotide formation 712083
Show all pathways known for 3.5.4.12Display the word mapDisplay the reaction diagram Show all sequences 3.5.4.12metabolism the enzyme is crucial to the production of dTTP needed for DNA replication and damage repair. It mediates dNTP pool balance required for normal chloroplast development and vegetative growth in plants 757330
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