EC Number   |
General Information |
Reference |
|---|
   3.5.1.78 | evolution |
phylogenetic distribution of Gss: Gss sequences are largely limited to certain bacteria and kinetoplastids, and are absent in a variety of invertebrate and vertebrate species, archaea, plants and some eubacteria |
727554 |
| 3.5.1.78 | evolution |
the synthetase domain of GspSA belongs to the class of ATP-grasp structural domains. Proteins YgiC and YjfC proteins show 51% identity between themselves and 28% identity to the synthetase domain of the GspSA enzyme, but do not show any glutathionylspermidine synthetase/amidase enzyme activity |
727627 |
| 3.5.1.78 | metabolism |
microarray studies comparing gss+ and DELTAgss strains of Escherichia coli show that a large number of genes are either upregulated (76 genes more than 3fold) or downregulated (35 genes more than 3fold) by the loss of the gss gene. Most significant categories of up-regulated genes include sulfur utilization, glutamine and succinate metabolism, polyamine and arginine metabolism, and purine and pyrimidine metabolism |
727554 |
| 3.5.1.78 | more |
comparison of catalytic properties of recombinant purified proteins GspSA, YgiC, and YjfC, overview |
727627 |
