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Results 1 - 10 of 15 > >>
EC Number General Information Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.65evolution enzyme Der p 1 is a cysteine protease from the papain family 731348
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.65evolution mannosylation is a unique feature of the allergens within the cysteine protease family of enzymes, e.g. Der 1 p, papain, and bromelain, while non-allergens of the family, e.g. calpain, and cysteine protease B do not show mannosylation in their carbohydrate patterns, staphopain B is also a cysteine protease protein, like Der p 1, but is an amannosylated antigen 732689
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.65more activation mechanism analysis of the two other serine proteases, Der p 6 (chymotrypsin-like) and Der p 9 (collagenase)zymogen by mite protease Der p 1, overview 731348
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.65more binding properties of in tobacco plant-produced I-rDer p 1 versus the IgE of patients sera are comparable to those obtained on Der p 1 preparation immobilized on a microarray 732955
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.65more Dermatophagoides farinae allergen Der f1 is one of the most important indoor allergens associated with allergic diseases in humans 732926
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.65more the enzyme is a group 1 mite allergen 731895
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.65more the enzyme is bound by the mannose receptor of dendritic cells, the recombinant enzyme binds stronger due to its higher degree of mannans compared to the native enzyme 732689
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.65more the Group 7 as well as the Group 2 mite allergens are structurally similar to different proteins in the TLR pathway 717698
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.65physiological function Der p 7 elicits strong IgE antibody and T-cell responses in mite allergic patients. Sensitization to house dust mite allergens is strongly correlated with asthma. The allergen function may contribute to allergenicity, e.g. the protease activity of Group 1 mite allergens, and the interaction with the innate immune system by Group 2 mite allergens 717698
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.65physiological function Der p1 activates the human receptor mas-related G-protein-coupled receptor X1 and the mouse homolog mas-related G-protein-coupled receptor C11. Der p1 also induces the release of IL-6 from heterologous cells expressing mas-related G-protein-coupled receptor X1 754147
Results 1 - 10 of 15 > >>