EC Number   |
General Information |
Reference |
|---|
    3.1.3.3 | malfunction |
enzyme knock-down disturbs nitrogen metabolism but does not disturb glycine and serine synthesis or sulfur assimilation and metabolism. Enzyme knock-down induces additional defense mechanisms against cadmium toxicity |
750674 |
| 3.1.3.3 | malfunction |
in a rat model of periodontal disease using a SerB mutant strain it is shown that the SerB phosphatase of Porphyromonas gingivalis is required for maximal alveolar bone resorption, and in the absence of SerB, more polymorphonuclear neutrophils are recruited into the gingival tissues |
715162 |
| 3.1.3.3 | malfunction |
knock down of PSPH dramatically diminishes squamous cell carcinoma cell proliferation and cyclin D1 levels in the presence of exogenous of L-serine production suggesting a non-canonical role for PSPH in epithelial carcinogenesis |
715741 |
| 3.1.3.3 | metabolism |
Hanks-type STKs and STPs play an essential role in the regulation of various cellular processes, by reversibly phosphorylating many protein targets, among them several regulatory proteins of other signaling cascades. High complexity of bacterial regulatory network, in which the crosstalk between STK/STP signaling enzymes, components of bacterial two-component systems (TCSs), and the translational machinery occurs. Physiological processes regulated by bacterial Hanks-type STKs and STPs in different bacteria, overview |
-, 750864 |
| 3.1.3.3 | physiological function |
reversible phosphorylation is a key mechanism that enables bacteria to sense and respond to changing environmental conditions. The corresponding kinase to enzyme PrpC is kinase RsbB. Enzyme RsbX is a PPM phosphatase. The phosphoserine phosphatase is involved in sigma B regulation and stress response |
-, 750864 |
| 3.1.3.3 | physiological function |
reversible phosphorylation is a key mechanism that enables bacteria to sense and respond to changing environmental conditions. The corresponding kinase to enzyme PrpC is kinase RsbV. Enzyme RsbU is a PPM phosphatase. The phosphoserine phosphatase is involved in energy stress response |
-, 750864 |
| 3.1.3.3 | physiological function |
reversible phosphorylation is a key mechanism that enables bacteria to sense and respond to changing environmental conditions. The corresponding kinase to enzyme PrpC is kinase RsbV. Enzyme RsbU is a PPM phosphatase. The phosphoserine phosphatase is involved in sigma B regulation and stress response |
-, 750864 |
| 3.1.3.3 | physiological function |
the embryo-lethal phenotype of isoform psp1 mutants can be complemented with PSP1 cDNA under the control of Pro35S. However, this construct is poorly expressed in the anther tapetum, and does not complement mutant fertility. Microspore development in psp1.1/psp1.1 mutants expressing Pro35S:PSP1 arrest at the polarized stage. The tapetum from these lines displays delayed and irregular development. In addition to embryo death and male sterility, conditional psp1 mutants display a short-root phenotype, which is reverted in the presence of serine |
730605 |
