EC Number   |
General Information |
Reference |
|---|
   3.1.21.3 | evolution |
Staphylococcus aureus displays a clonal population structure in which horizontal gene transfer between different lineages is extremely rare. This is due, in part, to the presence of a Type I DNA restriction-modification (RM) system given the generic name of Sau1, which maintains different patterns of methylation on specific target sequences on the genomes of different lineages. The determination of so many recognition sequences of Type I RM systems in different lineages of Staphylococcus aureus, means that now the population structure of Staphylococcus aureus can be investigated from an epigenetic/evolutionary perspective |
751739 |
| 3.1.21.3 | physiological function |
a type I restriction-modification system that is clade A1 specific, is active for DNA methylation, and significantly reduces the transformability of clade A1 Enterococcus faecium. The restriction-modification systems act as barriers to horizontal gene exchange in Enterococcus faecium and contribute to Enterococcus faecium subspecies separation |
749678 |
| 3.1.21.3 | physiological function |
EcoprrI is an apoptosis enzyme |
730505 |
| 3.1.21.3 | physiological function |
the EcoKI type I restriction-modification system in Escherichia coli affects the uptake of DNA by conjugation but is not a major barrier to plasmid transfer |
750960 |
| 3.1.21.3 | physiological function |
the type I restriction-modification system hsdS contributes to the Streptococcus suis serotype 2 survival ability in phagocytes. HsdS facilities anti-phagocytosis and survival in microglia and whole blood through positively impacting the expression of virulence-associated factors lysM and lysM', enhancing the survival ability against peroxidation environment, and reducing the TNF-alpha and NO production in microglia |
750631 |
