EC Number   |
General Information |
Reference |
|---|
   3.1.1.43 | evolution |
the enzyme belongs to the class of hydrolases with alpha/beta-type folding |
-, 730436 |
| 3.1.1.43 | evolution |
two major groups of alpha-amino acid ester hydrolases contain enzymes with a similar active center structure, which determines their unique specificity to esters containing an amino group in the alpha position to the carbonyl. The first group comprises microbial alpha-amino acid ester hydrolases of the beta-lactam acylase type. Technical biocatalysts based on this group of enzymes are used for the production of semisynthetic amino-beta-lactam antibiotics. The second alpha-amino acid ester hydrolases group includes eukaryotic valacyclovirases, which activate in vivo a number of antiviral and anticancer prodrugs. The enzyme from Acetobacter pasteurianus belongs to the first group |
-, 729021 |
| 3.1.1.43 | evolution |
two major groups of alpha-amino acid ester hydrolases contain enzymes with a similar active center structure, which determines their unique specificity to esters containing an amino group in the alpha position to the carbonyl. The first group comprises microbial alpha-amino acid ester hydrolases of the beta-lactam acylase type. Technical biocatalysts based on this group of enzymes are used for the production of semisynthetic amino-beta-lactam antibiotics. The second alpha-amino acid ester hydrolases group includes eukaryotic valacyclovirases, which activate in vivo a number of antiviral and anticancer prodrugs. The enzyme from Acetobacter turbidans belongs to the first group |
-, 729021 |
| 3.1.1.43 | evolution |
two major groups of alpha-amino acid ester hydrolases contain enzymes with a similar active center structure, which determines their unique specificity to esters containing an amino group in the alpha position to the carbonyl. The first group comprises microbial alpha-amino acid ester hydrolases of the beta-lactam acylase type. Technical biocatalysts based on this group of enzymes are used for the production of semisynthetic amino-beta-lactam antibiotics. The second alpha-amino acid ester hydrolases group includes eukaryotic valacyclovirases, which activate in vivo a number of antiviral and anticancer prodrugs. The enzyme from Flavobacterium sp. belongs to the first group |
-, 729021 |
| 3.1.1.43 | evolution |
two major groups of alpha-amino acid ester hydrolases contain enzymes with a similar active center structure, which determines their unique specificity to esters containing an amino group in the alpha position to the carbonyl. The first group comprises microbial alpha-amino acid ester hydrolases of the beta-lactam acylase type. Technical biocatalysts based on this group of enzymes are used for the production of semisynthetic amino-beta-lactam antibiotics. The second alpha-amino acid ester hydrolases group includes eukaryotic valacyclovirases, which activate in vivo a number of antiviral and anticancer prodrugs. The enzyme from Gluconobacter suboxydans belongs to the first group |
-, 729021 |
| 3.1.1.43 | evolution |
two major groups of alpha-amino acid ester hydrolases contain enzymes with a similar active center structure, which determines their unique specificity to esters containing an amino group in the alpha position to the carbonyl. The first group comprises microbial alpha-amino acid ester hydrolases of the beta-lactam acylase type. Technical biocatalysts based on this group of enzymes are used for the production of semisynthetic amino-beta-lactam antibiotics. The second alpha-amino acid ester hydrolases group includes eukaryotic valacyclovirases, which activate in vivo a number of antiviral and anticancer prodrugs. The enzyme from Mycoplana dimorpha belongs to the first group |
-, 729021 |
| 3.1.1.43 | evolution |
two major groups of alpha-amino acid ester hydrolases contain enzymes with a similar active center structure, which determines their unique specificity to esters containing an amino group in the alpha position to the carbonyl. The first group comprises microbial alpha-amino acid ester hydrolases of the beta-lactam acylase type. Technical biocatalysts based on this group of enzymes are used for the production of semisynthetic amino-beta-lactam antibiotics. The second alpha-amino acid ester hydrolases group includes eukaryotic valacyclovirases, which activate in vivo a number of antiviral and anticancer prodrugs. The enzyme from Protaminobacter alboflavus belongs to the first group |
-, 729021 |
| 3.1.1.43 | evolution |
two major groups of alpha-amino acid ester hydrolases contain enzymes with a similar active center structure, which determines their unique specificity to esters containing an amino group in the alpha position to the carbonyl. The first group comprises microbial alpha-amino acid ester hydrolases of the beta-lactam acylase type. Technical biocatalysts based on this group of enzymes are used for the production of semisynthetic amino-beta-lactam antibiotics. The second alpha-amino acid ester hydrolases group includes eukaryotic valacyclovirases, which activate in vivo a number of antiviral and anticancer prodrugs. The enzyme from Pseudomonas danceae belongs to the first group |
729021 |
| 3.1.1.43 | evolution |
two major groups of alpha-amino acid ester hydrolases contain enzymes with a similar active center structure, which determines their unique specificity to esters containing an amino group in the alpha position to the carbonyl. The first group comprises microbial alpha-amino acid ester hydrolases of the beta-lactam acylase type. Technical biocatalysts based on this group of enzymes are used for the production of semisynthetic amino-beta-lactam antibiotics. The second alpha-amino acid ester hydrolases group includes eukaryotic valacyclovirases, which activate in vivo a number of antiviral and anticancer prodrugs. The enzyme from Pseudomonas melanogenum belongs to the first group |
-, 729021 |
| 3.1.1.43 | evolution |
two major groups of alpha-amino acid ester hydrolases contain enzymes with a similar active center structure, which determines their unique specificity to esters containing an amino group in the alpha position to the carbonyl. The first group comprises microbial alpha-amino acid ester hydrolases of the beta-lactam acylase type. Technical biocatalysts based on this group of enzymes are used for the production of semisynthetic amino-beta-lactam antibiotics. The second alpha-amino acid ester hydrolases group includes eukaryotic valacyclovirases, which activate in vivo a number of antiviral and anticancer prodrugs. The enzyme from Xanthomonas citri belongs to the first group |
-, 729021 |
