EC Number   |
General Information |
Reference |
|---|
   2.7.8.B11 | malfunction |
Escherichia coli has three cardiolipin synthases. Cardiolipin synthase A encoded by clsA, cardiolipin synthase B encoded by clsB and cardiolipin synthase C, encoded by clsC. Triple deletions of clsA, clsB, and clsC results in the complete depletion of cardiolipin synthase activity in Escherichia coli cells. The double mutant DELTAclsAB mutant still makes cardiolipin in the stationary phase |
728679 |
| 2.7.8.B11 | physiological function |
a modest increase of cardiolipin content is observed in the ClsC overexpression strain. Phosphatidylethanolamine and phosphatidylglycerol levels remain unaltered upon overexpression of ClsC, and levels of phosphatidylalcohols are unaltered in the ClsC knockout mutant |
760626 |
| 2.7.8.B11 | physiological function |
Escherichia coli has three cardiolipin synthases. All cardiolipin synthases contribute cardiolipin the stationary phase. Only cardiolipin synthase A makes detectible cardiolipin in low-osmolarity medium during logarithmic growth and contributes the majority of cardiolipin in high-osmolarity medium |
728679 |
