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EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 2.7.8.45physiological function gene product TarF is essential for viability. Staphylococcus aureus shows a lethal gain-of-function mechanism where lesions beyond the initial step in wall teichoic acid biosynthesis render Staphylococcus aureus nonviable -, 740607
Display the reaction diagram Show all sequences 2.7.8.45physiological function gene products TarA, TarB, TarF, and TarL are required to convert the GlcNAc-diphosphate-lipid product of TarO to the full-length polyribitol polymer -, 740296
Display the reaction diagram Show all sequences 2.7.8.45physiological function Staphylococcus aureus requires a glycerol-phosphate primase called TarF in order make polyribitol-phosphate-wall teichoic acids. TarF is essentisal in wild-type background but can be deleted in a strain expression Bacillus subtilis TarK-TarL -, 740298
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