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2.7.8.34
malfunction
deleting the gene encoding the key enzyme in di-myo-inositol phosphate synthesis, CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase, abolishes di-myo-inositol phosphate synthesis. Mutants deficient in di-myo-inositol phosphate use aspartate to cope with heat stress
708934
2.7.8.34
physiological function
di-myo-inositol phosphate is part of the strategy used by Thermococcus kodakarensis to cope with heat stress. Aspartate can be used as an alternative solute of similar efficacy
708934
2.7.8.34
physiological function
the enzyme is involved in synthesis of di-myo-inositol phosphate. Archaeoglobus fulgidus accumulates di-myo-inositol phosphate and diglycerol phosphate in response to heat and osmotic stresses, respectively, and the level of glycero-phospho-myo-inositol increases primarily when the two stresses are combined
687375
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