EC Number |
General Information |
Reference |
---|
2.7.7.24 | malfunction |
btrD mutant shows no production of any antibiotics under the standard fermentation conditions, while the complementation of this disruption by transformation recovers the antibiotic production |
719642 |
2.7.7.24 | malfunction |
knockdown of rml-1, rml-4 and rml-5 (but not rml-2 and rml-3) causes lethality of the embryo |
747027 |
2.7.7.24 | metabolism |
rml-1 and gmp-1 are essential in embryogenesis and larval development |
747027 |
2.7.7.24 | metabolism |
the enzyme is involved in the biosynthesis of the dTDP-3-amino-3,6-dideoxy-D-galactose and dTDP-3-amino-3,6-dideoxy-D-glucose |
747917 |
2.7.7.24 | metabolism |
the enzyme is involved in the dTDP-rhamnose biosynthetic pathway |
747027 |
2.7.7.24 | metabolism |
UTP/dTTP-glucose-1-phosphate uridylyl/thymidylyl transferase RML-1 converts alpha-D-glucose 1-phosphate in the presence of dTTP or UTP into dTDP-Glc or UDP-Glc, respectively. The dTDP-Glc is used for the biosynthesis of rhamnose in Caenorhabditis elegans, whereas the UDP-Glc may be used in the biosynthesis of glycogen, glycolipids and/or N-glycans |
747027 |
2.7.7.24 | physiological function |
btrD gene is involved in the butirosin biosynthesis |
719642 |
2.7.7.24 | physiological function |
the enzyme catalyzes the first step in the biosynthesis of L-rhamnose, which is a deoxysugar critical for the integrity of the bacterium's cell wall |
-, 762339 |
2.7.7.24 | physiological function |
the multifunctional enzyme is involved in biosynthesis of UDP-N-acetyl-alpha-D-glucosamine, an activated and essential form of N-acetyl-alpha-D-glucosamine that is an important component in the polysaccharide structure of most organisms |
-, 725308 |