EC Number   |
General Information |
Reference |
|---|
    2.7.1.2 | drug target |
glucokinase from pathogenic protozoa of the genus Leishmania is a potential drug target for the chemotherapeutic treatment against leishmaniasis because this enzyme is located at a nodal point between two critically important metabolic pathways, glycolysis and the pentose phosphate pathway |
759749 |
| 2.7.1.2 | malfunction |
chromosomal deletion of the glk gene resulted in a loss of glucokinase activity and retardation of growth as well as in a decrease of intracellular glycogen content |
-, 758660 |
| 2.7.1.2 | metabolism |
the abundance enzme is attenuated when culture temperature is elevated and is almost undetectable at 80°C. The glucokinase interacts with heat shock protein HSP60 at 60°C and 75°C |
-, 737805 |
| 2.7.1.2 | metabolism |
the enzyme implicated in the regulation of glycogen biosynthesis and degradation in an obligate methanotroph |
-, 758660 |
| 2.7.1.2 | metabolism |
the enzyme is an essential component required for glucose signaling |
-, 759365 |
| 2.7.1.2 | metabolism |
the enzyme is located at a nodal point between two critically important metabolic pathways, glycolysis and the pentose phosphate pathway |
759749 |
| 2.7.1.2 | metabolism |
the enzyme plays a role in metabolism of nutrients acquired from the environment through either predation or directly from the sediment |
758654 |
