EC Number   |
General Information |
Reference |
|---|
    2.7.1.148 | metabolism |
CDPME kinase (IspE) catalyzes the phosphorylation of CDPME to 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDPME2P) as part of the MEP pathway, overview. In Bacillus subtilis, no stable complexes of BsIspD/BsIspE, BsIspD/BsIspF, and BsIspD/BsIspE/BsIspF are observed, interaction analysis, overview |
-, 747328 |
| 2.7.1.148 | metabolism |
CDPME kinase (IspE) catalyzes the phosphorylation of CDPME to 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDPME2P) as part of the MEP pathway, overview. In Escherichia coli, no stable complexes of EcIspD/EcIspE, EcIspE/EcIspF, and EcIspD/EcIspE/EcIspF are observed, only the dual mixture of BsIspE and BsIspF seems to merge into a single band, interaction analysis, overview |
747328 |
| 2.7.1.148 | metabolism |
enzyme catalyses the fourth reaction step of the 2C-methylerythritol 4-phosphate (MEP) pathway for the biosynthesis of isopentenyl pyrophosphate and its isomer dimethylallyl pyrophosphate |
699633 |
| 2.7.1.148 | metabolism |
key enzyme in the biosynthesis pathway of terpenoids |
739765 |
| 2.7.1.148 | metabolism |
the enzyme 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase is the fourth enzyme in the methyl erythritol phosphate pathway (MEP pathway) of plant terpenoid biosynthesis |
762521 |
| 2.7.1.148 | more |
three-dimensional structure and active site structure predictions. The active site of PvIspE consists of total 32 amino acid residues, 16 amino acid residues involved in ATP binding (Y225, P226, D230, N231, I232, K258, I262, F263, S264, G265, G267, G268, G269, N272, D304, S349) and 16 amino acid residues interacts with the substrate CDM (K136, N138, L141, H150, N151, M157, S270, G302, S303, D304, K319, S349, R350, Y353, L413, G444) |
-, 762094 |
| 2.7.1.148 | physiological function |
CDPME kinase (IspE) catalyzes the phosphorylation of CDPME to 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDPME2P) |
-, 747328 |
| 2.7.1.148 | physiological function |
involved in terpenoid metabolism |
706809 |
| 2.7.1.148 | physiological function |
the MEP pathway is essential in the malaria parasite Plasmodium falciparum and in most eubacteria, including the causal agents for diverse and serious human diseases like leprosy, bacterial meningitis, various gastrointestinal and sexually transmitted infections, tuberculosis, and certain types of pneumonia |
699633 |
