EC Number   |
General Information |
Reference |
|---|
    2.5.1.32 | evolution |
Euglena gracilis CrtB belongs to a clade that is distinct from groups of algae and higher plants |
-, 737951 |
| 2.5.1.32 | malfunction |
RNA interference-based gene silencing of phytoene synthase impairs growth, carotenoids, and plastid phenotype in Oncidium hybrid orchid. PSY-RNAi in transgenic Oncidium alters the expression pattern of biosynthetic pathway and leads to decreased accumulation of carotenoid contents. The transgenic orchids show downregulated level of enzyme PSY and geranyl synthase gene. They display semi-dwarf phenotype, brilliant green leaves, and development-arrested plastids with rare grana. The total carotenoid content is decreased and the efficiency of the photosynthetic electron transport is declined. The chlorophyll level and the expression of chlorophyll biosynthetic genes, such as OgGLUTR and OgCS are dramatically reduced. The endogenous level of gibberellic acid and abscisic acid in the dwarf transformants are 4fold lower than in wild-type plants. Chilling tolerance of the transgenic Oncidium plants is reduced |
739712 |
| 2.5.1.32 | malfunction |
the recessive mutation yellow-flesh (locus r) in tomato eliminates fruit carotenoids by disrupting the activity of the fruit-specific phytoene synthase, PSY1, allele r2997 of yellow-flesh eliminates transcription of PSY1 in fruits. Fruits of the recessive mutation tangerine (t) appear orange due to accumulation of 7,9,7',9'-tetra-cis-lycopene (prolycopene) as a result of a mutation in the carotenoid cis-trans isomerase, tangerine is epistatic to yellow-flesh, interaction between tangerine and yellow-flesh at the molecular level, overview |
723654 |
| 2.5.1.32 | metabolism |
carotenogenesis is regulated by 5'UTR-mediated translation of phytoene synthase splice variants. Arabidopsis thaliana possess a single phytoene synthase gene. This monogenic situation is compensated by the differential expression of two alternative splice variants, which differ in length and in the exon/intron retention of their 5'UTRs |
759976 |
| 2.5.1.32 | metabolism |
catalyzation of the first two steps of the carotenoid biosynthesis |
706238 |
| 2.5.1.32 | metabolism |
first step in the biosynthesis of alpha-carotene, beta-carotene, and lutein |
704734 |
| 2.5.1.32 | metabolism |
key enzyme in carotenoid biosynthesis |
760175 |
| 2.5.1.32 | metabolism |
light-sensitive phytochrome-interacting factors are not required to regulate phytoene synthase gene expression in the root |
739376 |
| 2.5.1.32 | metabolism |
phytoene synthase is the first rate-limiting regulatory enzyme in the carotenoid biosynthesis pathway |
739712 |
| 2.5.1.32 | metabolism |
PSY1 catalyzes the first committed step in the carotenoid biosynthesis pathway, the formation of phytoene from two molecules of geranylgeranyl diphosphate |
723654 |
