EC Number   |
General Information |
Reference |
|---|
   2.4.2.31 | malfunction |
enzyme gene silencing inhibits the growth of the spleen transplanted CT-26 colon carcinoma tumor and its ability to spread to the liver via metastasis |
759782 |
| 2.4.2.31 | malfunction |
enzyme knockdown increases apoptosis of CT-26 cells transplant tumor. Furthermore, the activity of Akt and Erk cell signal pathways and expression of an apoptosis biomarker, betaIIItubulin, decrease when the enzyme is silenced |
737293 |
| 2.4.2.31 | malfunction |
enzyme silencing induces hypermethylation of the urokinase plasminogen activator gene |
759354 |
| 2.4.2.31 | malfunction |
enzyme silencing inhibits PARP 1 expression by decreasing the expression of nuclear factor-kappaB, inhibiting ras homolog A |
736266 |
| 2.4.2.31 | physiological function |
ADP-ribosylation of the P2X7(k) but not the P2X7(a) variant induces stable Ca2+ signals |
723579 |
| 2.4.2.31 | physiological function |
avian orthologue of the acatalytic mammalian ART4 is a mono-ADP-ribosyltransferase with enzymatic activity comparable to that of other, catalytically active and glycosyl-phosphatidylinositol-anchored members of the mammalian ART family |
702911 |
| 2.4.2.31 | physiological function |
enzyme is an actin-specific ADP-ribosyltransferase, called binary toxin CDT, present in about 6% of strains isolated from patients with suspected Peptoclostridium difficile-associated diarrhea or colitis. All binary toxin-positive strains tested also produce toxins TcdB and/or TcdA. However, they have significant changes in the tcdA and tcdB genes and belong to variant toxinotypes III, IV, V, VII, IX, and XIII |
728041 |
| 2.4.2.31 | physiological function |
enzyme over-expression causes hypomethylation of the urokinase plasminogen activator gene. The enzyme is related to the expression and activity of DNA methyltransferase 1 |
759354 |
| 2.4.2.31 | physiological function |
expression of Art7.1 molecules on B-cells can modulate the B cell receptor signalling and direct the B-cell fate to maturation |
705674 |
| 2.4.2.31 | physiological function |
high level of enzyme expression decreases the apoptosis rate of CT-26 cells induced by cisplatin |
736914 |
