EC Number |
General Information |
Reference |
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2.3.1.99 | evolution |
the enzyme belongs to the superfamily of BAHD acyltransferases. The conserved sequence motifs HxxxDG and DFGWG are surrounded by differing amino acid environments which show typical features for hydroxycinnamoyl-CoA:hydroxyphenyllactic acid hydroxycinnamoyltransferase, RAS, and hydroxycinnamoyl-CoA:shikimic acid hydroxycinnamoyltransferase/hydroxycinnamoyl-CoA:quinate hydroxycinnamoyltransferase, HST/HQT |
720787 |
2.3.1.99 | metabolism |
HQT is involved in one of three possible pathways of chlorogenate biosynthesis, overview |
720778 |
2.3.1.99 | metabolism |
polyphenol metabolism and chlorogenic acid synthesis pathway involving the enzyme, overview |
702918 |
2.3.1.99 | metabolism |
quinate is used as acceptor molecule by a HQT and 4-coumaroylquinate is formed, which is hydroxylated by a member of the CYP98A family to chlorogenic acid |
720787 |
2.3.1.99 | physiological function |
constitutive expression of HQT in Arabidopsis thaliana results in the production of 5-caffeoylquinic acid in the leaf and an higher level of resistance to the bacterial pathogen Pseudomonas syringae. 5-caffeoylquinic acid synthesis is positively correlated with HQT transcript abundance |
756137 |
2.3.1.99 | physiological function |
expression in Nicotiana tabacum causes a higher total production of chlorogenic acids |
758066 |
2.3.1.99 | physiological function |
in callus of recombinant Lonicera japonica, there is a positive correlation between chlorogenic acid content and the expression of Hqt |
758061 |
2.3.1.99 | physiological function |
Taraxacum antungense lines overexpressing HQT increases chlorogenic acid but not caffeic acid concentrations. The chlorogenic acid concentration is significantly higher in the leaves than in the roots. The overexpression lines are more salt resistant than the wild-type and RNAi lines |
-, 757932 |