EC Number   |
General Information |
Reference |
|---|
    2.3.1.8 | metabolism |
anaerobic fermentative metabolism of glycerol. Proteome analysis as well as enzyme assays performed in cell-free extracts demonstrate that glycerol is degraded via glyceraldehyde-3-phosphate, which is further metabolized through the lower part of glycolysis leading to formation of mainly ethanol and hydrogen |
748573 |
| 2.3.1.8 | physiological function |
expression of phosphate acetyltransferase eutD restOres the ability of a strain lacking phosphate acetyltransferase pta and acetate kinase to grow on acetate as sole carbon source |
720217 |
| 2.3.1.8 | physiological function |
the phosphotransacetylase Pta and acetate kinase Ack genes are tandemly located in the genome, and are cotranscribed as an operon. Inactivation of Pta or Ack by homologous recombination is successful only when the inactivated gene is expressed in trans |
-, 757471 |
| 2.3.1.8 | physiological function |
the substrate-binding site is located at the C-terminal PTA-PTB domain. The N-terminal P-loop NTPase domain is involved in expression of the maximal catalytic activity, stabilization of the hexameric native state, and phosphate acetyltransferase activity regulation by NADH, ATP, phosphoenolpyruvate, and pyruvate. The truncated protein Pta-F3 is able to complement the growth on acetate of an Escherichia coli mutant defective in acetyl-CoA synthetase and phosphate acetyltransferase activity |
719451 |
