Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search General Information

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 4 of 4
download as CSV
download all results as CSV
EC Number General Information Commentary Reference
Display the reaction diagram Show all sequences 2.3.1.244malfunction a lovF mutant strain produces no lovastatin 441506
Display the reaction diagram Show all sequences 2.3.1.244metabolism the enzyme is involved in the lovastatin biosynthetic pathway 731290
Display the reaction diagram Show all sequences 2.3.1.244metabolism thne enzyme is involved in lovastatin biosynthesis 441506
Display the reaction diagram Show all sequences 2.3.1.244physiological function enzyme LovF synthesizes the alpha-S-methylbutyrate side chain that is subsequently transferred to monacolin J to yield the cholesterol-lowering natural product lovastatin. The diketide product of LovF is offloaded from the LovF acyl carrier protein domain by the dissociated acyltransferase LovD. LovD primarily interacts with the acyl carrier protein domain of LovF and the protein-protein interactions lead to highly efficient transfer of the diketide product. The catalytic efficiency is enhanced nearly one millionfold when LovF is used as the acyl carrier instead of N-acetylcysteamine 729881
Results 1 - 4 of 4
download as CSV
download all results as CSV