EC Number   |
General Information |
Reference |
|---|
   2.3.1.217 | evolution |
the enzyme belongs to the Type III polyketide synthase family |
719850, 722740 |
| 2.3.1.217 | evolution |
the enzyme belongs to the Type III polyketide synthase family. A Cys-His-Asn catalytic triad is conserved in all known type III PKSs |
719493 |
| 2.3.1.217 | evolution |
the enzyme belongs to the type III polyketide synthase family. A Cys-His-Asn catalytic triad is conserved in all known type III polyketide synthases |
719493 |
| 2.3.1.217 | metabolism |
the enzyme catalyzes a step in the curcuminoid biosynthesis, pathway overview |
719850, 722740 |
| 2.3.1.217 | more |
active site residue His303 is important for 2-oxoacid condensation, involvement of the hydrophobic cavity around Phe265 in 2-oxoacid condensation, wild-type and mutant ligand binding structures and structure-function relationship, modeling, overview |
722740 |
| 2.3.1.217 | more |
CURS can collaborate with curcumin synthase, DCS, EC 2.3.1.218, which provides the substrate feruloylacetyl-CoA from condensation of feruloyl-CoA and malonyl-CoA, overview |
719850 |
