EC Number   |
General Information |
Reference |
|---|
  2.3.1.207 | evolution |
FabY belongs to the KASIII domain containing enzymes |
719743 |
| 2.3.1.207 | malfunction |
the fabY deletion strain grows slowly in comparison to the fabHEc exchange control without C10 supplementation |
719743 |
| 2.3.1.207 | metabolism |
the KASIII domain-containing enzyme FabY from open reading frame PA3286 shunts fatty acid degradation intermediates from the beta-oxidation pathway by condensing octanoyl-CoA with malonyl-ACP to make beta-keto-decanoyl-ACP, a key building block common to saturated fatty acids, unsaturated fatty acids, and lipopolysaccharides |
719743 |
| 2.3.1.207 | physiological function |
FabY, a beta-ketoacyl synthase KASI/II domain-containing enzyme that condenses acetyl-CoA with malonyl-acyl carrier protein (ACP) to make the fatty acid synthesis, FAS, primer beta-acetoacetyl-ACP. FabY is an enzyme required for FAS initiation in the absence of exogenous fatty acids |
719743 |
