EC Number |
General Information |
Reference |
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2.1.1.254 | malfunction |
disruption of the transcription unit, herein designated eryG, by insertion of an integrational plasmid vector, causes a block at the terminal step in the biosynthesis of erythromycin, the conversion of erythromycin C to A by 0-methylation |
715107 |
2.1.1.254 | malfunction |
eryG mutant strain lacks detectable erythromycin O-methyltransferase activity with erythromycin C, erythromycin D, or the analogs 2-norerythromycin C and 2-norerythromycin D as substrates |
715327 |
2.1.1.254 | malfunction |
the eryG mutation affects the conversion of L-mycarose to L-cladinose |
716130 |
2.1.1.254 | physiological function |
the enzyme catalyzes all of the 3''-O-methylation reactions of the erythromycin biosynthetic pathway in Saccharopolyspora erythraea |
715327 |