EC Number   |
General Information |
Reference |
|---|
   2.1.1.245 | metabolism |
the enzyme reaction initiates the unusual biological organometallic reaction sequence that constitutes the Wood-Ljungdahl or reductive acetyl-CoA pathway |
717236 |
| 2.1.1.245 | more |
genes cdhD and cdhE encode the delta and gamma subunits of the C/Fe-S enzyme from the CO dehydrogenase complex of Methanosarcina thermophila, the complex comprises a nickel/iron-sulfur, Ni/Fe-S, enzyme containing alpha and epsilon subunits and a corrinoid/iron-sulfur, C/Fe-S, enzyme containing gamma and delta subunits. The C/Fe-S enzyme contains one molecule of factor III in the base-off form which facilitates reduction of the cobalt atom to the Co1+ redox state, which is a requirement for methylation. The gamma subunit CdhE contains the single 4Fe-4S center in the C/Fe-S enzyme, overview |
717714 |
| 2.1.1.245 | more |
genes cdhD and cdhE encode the delta and gamma subunits of the C/Fe-S enzyme from the CO dehydrogenase complex of Methanosarcina thermophila, the complex comprises a nickel/iron-sulfur, Ni/Fe-S, enzyme containing alpha and epsilon subunits and a corrinoid/iron-sulfur, C/Fe-S, enzyme containing gamma and delta subunits. The C/Fe-S enzyme purified contains one molecule of factor III in the base-off form which facilitates reduction of the cobalt atom to the Co1+ redox state, which is a requirement for methylation. The gamma subunit CdhE contains the single 4Fe-4S center in the C/Fe-S enzyme |
717714 |
| 2.1.1.245 | more |
loss of acetyl-CoA synthesis activity of the beta-subunit of the enzyme complex does not influence the gamma and delta subunit activities |
717755 |
