EC Number   |
General Information |
Reference |
|---|
    1.5.3.17 | evolution |
AtPAO2-AtPAO4 form a subfamily of polyamine oxxidases different from AtPAO1, EC 1.5.3.16, overview |
-, 725625 |
| 1.5.3.17 | evolution |
identification of four polyamine oxidase subfamilies in plants. Subfamily PAO back conversion 1 (PAObc1) is present on every lineage included in these analyses. Subfamily PAObc2 is exclusively present in vascular plants. The only terminal catabolism (TC) PAO subfamily was lost in Superasterids but it is present in all other land plants. Subfamily PAObc3 is the result of a gene duplication event preceding Angiosperm diversification, followed by a gene extinction in Monocots. Differential conserved protein motifs exist for each subfamily of plant PAOs |
764377 |
| 1.5.3.17 | malfunction |
loss-of-function mutants contain 2-fold higher thermospermine levels and exhibit delayed transition from vegetative to reproductive growth compared with that of wild-type plants |
743491 |
| 1.5.3.17 | malfunction |
loss-of-function of AtPAO gene results to increased NADPH-oxidase-dependent production of superoxide anions but not H2O2, which activates the mitochondrial alternative oxidase pathway (AOX). On the contrary, overexpression of AtPAO3 results in an increased but balanced production of both H2O2 and superoxide anions |
742588 |
| 1.5.3.17 | malfunction |
two loss-of-function atpao5 mutants and a 35S::AtPAO5 Arabidopsis transgenic line present phenotypical differences from the wild-type plants with regard to stem and root elongation, differences that are accompanied by changes in polyamine levels and the number of xylem vessels. It is shown that cytokinin treatment, which up-regulates AtPAO5 expression in roots, differentially affects protoxylem differentiation in 35S::AtPAO5, atpao5, and wild-type roots |
743004 |
| 1.5.3.17 | metabolism |
residues Gln94, Tyr403 and Thr440 are predicted to be important in the active site |
765603 |
| 1.5.3.17 | metabolism |
the enzyme contributes to abscisic acid mediated plant developmental processes |
743529 |
| 1.5.3.17 | metabolism |
the enzyme is involved in the polyamine back-conversion pathway, overview |
-, 725625 |
| 1.5.3.17 | more |
His64 hydrogen bonds to the reactive nitrogen in the polyamine substrate |
724126 |
| 1.5.3.17 | more |
the active site of Fms1 contains three amino acid residues positioned to interact with the polyamine substrate, His67, Asn195, and Asp94. These three residues form a hydrogen-bonding triad with Asn195 being the central residue. His67 is important both for interacting with the substrate and for maintaining the hydrogen bonds in the triad |
724359 |
