EC Number   |
General Information |
Reference |
|---|
    1.3.2.3 | malfunction |
a change in ascorbic acid content caused by silencing or overexpressing GLDH, respectively, in rice plants leads to a changed plant growth and seed set |
723888 |
| 1.3.2.3 | malfunction |
analysis of the vtc2-1 mutant shows that complex I assembly is not affected in this mutant, while it is affected in the mutant ndufs4 of NADH dehydrogenase [ubiquinone] iron-sulfur protein 4 of Arabidopsis thaliana Col-0, in ndufs4, complex I is not assembled and GLDH is not present in any intermediate larger than 450 kDa. This suggests that the 450 kDa intermediate is a precursor of complex I. Very low amounts of complex I and other assembly intermediates in the gldh mutant, suggesting that the assembly of complex I is not completely arrested, but it is severely impaired in the absence of GLDH |
-, 746093 |
| 1.3.2.3 | malfunction |
ascorbic acid deficiency in L-GalLDH-suppressed transgenic rice, GI-1 and GI-2, which have constitutively low (between 30% and 50%) leaf and grain ascorbic acid content compared with the wild-type, leads to increased grain chalkiness in the transgenic rice. Deficiency of ascorbic acid also results in a higher lipid peroxidation and H2O2 content, accompanied by a lower hydroxyl radical scavenging rate, total antioxidant capacity and photosynthetic ability. Changes of the enzyme activities and gene transcript abundances related to starch synthesis are also observed in GI-1 and GI-2 grains. Phenotypes, detailed overview |
745635 |
| 1.3.2.3 | malfunction |
decreasing TaGLDH expression in wheat significantly reduces GLDH activity and ascorbic acid content, but in the leaf tissues undergoing TaGLDH silencing, the reductions of total and reduced ascorbic acid contents are considerably below the decreases in TaGLDH expression and GLDH activity. Association of the mutant TaGLDH-A1b variant with enhanced tolerance to water deficiency stress, overview |
746491 |
| 1.3.2.3 | malfunction |
GLDH-suppressed transgenic rices, GI-1 and GI-2, which have constitutively low (between 30% and 50%) leaf ascorbic acid content compared with the wild-type plants, exhibit a significantly reduced tiller number |
725802 |
| 1.3.2.3 | malfunction |
homozygous Arabidopsis thaliana mutant gldhRNAi3-11 plants show approximately 40% of the GLDH activity of wild-type controls and are viable under standard laboratory conditions. Mutant gldhRNAi3-11 plants show about 20% decrease in the contents of reduced ascorbic acid and total ascorbic acid. Partial suppression of GLDH activity confers significant reduction in leaf water loss through decreasing stomatal aperture size in Arabidopsis thaliana, phenotype, overview |
-, 746068 |
| 1.3.2.3 | malfunction |
overexpression of L-galactono-gamma-lactone dehydrogenase increases vitamin C, total phenolics and antioxidant activity in lettuce through bio-fortification |
726154 |
| 1.3.2.3 | malfunction |
transgenic tobacco plants overexpressing GalLDH show an enhanced GalLDH transcript levels, GalLDH activities, and L-ascorbic acid accumulation as compared to wild-type plants. Abiotic stress tolerance is enhanced in transgenic plants compared to wild-type plants |
723894 |
| 1.3.2.3 | metabolism |
GLDH catalyzes the last step of L-ascorbate, AsA, biosynthesis in plants, but the upstream genes in the AsA biosynthetic pathway are responsible for enhancing the AsA content in plants, regulation, overview |
713264 |
| 1.3.2.3 | metabolism |
L-galactono-1,4-lactone dehydrogenase is one of the enzymes of the Smirnoff-Wheeler's branch of ascorbic acid biosynthetic pathway, overview |
746064 |
