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1.3.1.100
malfunction
disruption of the easA gene leads to accumulation of chanoclavine-I and chanoclavine-I-aldehyde
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721342
1.3.1.100
metabolism
the enzyme is required for incorporation of chanoclavine-I-aldehyde into more-complex ergot alkaloids, presumably by reducing the double bond conjugated to the aldehyde group, thus facilitating ring closure
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721342
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